A genetic framework controlling the differentiation of intestinal stem cells during regeneration in Drosophila.

The speed of stem cell differentiation has to be properly coupled with self-renewal, both under basal conditions for tissue maintenance and during regeneration for tissue repair. Using the Drosophila midgut model, we analyze at the cellular and molecular levels the differentiation program required f...

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Bibliographic Details
Main Authors: Zongzhao Zhai, Jean-Philippe Boquete, Bruno Lemaitre
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-06-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC5510897?pdf=render