SURVIVAL AND EVOLUTION OF CRISPR-CAS SYSTEM IN PROKARYOTES AND ITS APPLICATIONS

SURVIVAL AND EVOLUTION OF CRISPR-CAS SYSTEM IN PROKARYOTES AND ITS APPLICATIONS

Prokaryotes have developed numerous innate immune mechanisms in order to fend off bacteriophage or plasmid attack. One of these immune systems is Clustered regularly interspaced short palindromic repeats (CRISPR). CRISPR associated proteins play a key role in survival of prokaryotes against invaders...

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Bibliographic Details
Main Authors: Muhammad Abu Bakr Shabbir, Haihong Hao, Muhammad Zubair Shabbir, HAFIZ IFTIKHAR HUSSAIN, Zahid Iqbal, Saeed Ahmed, Adeel Sattar, Mujahid Iqbal, Jun Li, Zonghui Yuan
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-09-01
Series:Frontiers in Immunology
Subjects:
Gene Expression
CRISPR-Cas
Cas9
gene editing
SgRNA
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00375/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00375/full

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