Oscillations in MAPK cascade triggered by two distinct designs of coupled positive and negative feedback loops

<p>Abstract</p> <p>Background</p> <p>Feedback loops, both positive and negative are embedded in the Mitogen Activated Protein Kinase (MAPK) cascade. In the three layer MAPK cascade, both feedback loops originate from the terminal layer and their sites of action are eith...

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Bibliographic Details
Main Authors: Sarma Uddipan, Ghosh Indira
Format: Article
Language:English
Published: BMC 2012-06-01
Series:BMC Research Notes
Online Access:http://www.biomedcentral.com/1756-0500/5/287