Migration through a small pore disrupts inactive chromatin organization in neutrophil-like cells

Migration through a small pore disrupts inactive chromatin organization in neutrophil-like cells

Abstract Background Mammalian cells are flexible and can rapidly change shape when they contract, adhere, or migrate. The nucleus must be stiff enough to withstand cytoskeletal forces, but flexible enough to remodel as the cell changes shape. This is particularly important for cells migrating throug...

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Bibliographic Details
Main Authors: Elsie C. Jacobson, Jo K. Perry, David S. Long, Ada L. Olins, Donald E. Olins, Bryon E. Wright, Mark H. Vickers, Justin M. O’Sullivan
Format: Article
Language:English
Published: BMC 2018-11-01
Series:BMC Biology
Subjects:
Migration
Heterochromatin
Transcription
Chromatin conformation
Epigenetics
Mechanotransduction
Online Access:http://link.springer.com/article/10.1186/s12915-018-0608-2

Internet

http://link.springer.com/article/10.1186/s12915-018-0608-2

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