ACE2, the Counter-Regulatory Renin–Angiotensin System Axis and COVID-19 Severity

Angiotensin (ANG)-converting enzyme (ACE2) is an entry receptor of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes coronavirus disease 2019 (COVID-19). ACE2 also contributes to a deviation of the lung renin–angiotensin system (RAS) towards its counter-regulatory axis, thus t...

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Bibliographic Details
Main Authors: Filippos Triposkiadis, Andrew Xanthopoulos, Grigorios Giamouzis, Konstantinos Dean Boudoulas, Randall C. Starling, John Skoularigis, Harisios Boudoulas, Efstathios Iliodromitis
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Journal of Clinical Medicine
Subjects:
Online Access:https://www.mdpi.com/2077-0383/10/17/3885