N-docosahexaenoylethanolamine reduces neuroinflammation and cognitive impairment after mild traumatic brain injury in rats

Abstract At present, there is a growing interest in the study of the neurotropic activity of polyunsaturated fatty acids ethanolamides (N-acylethanolamines). N-docosahexaenoylethanolamine (DHEA, synaptamide) is an endogenous metabolite and structural analogue of anandamide, a widely studied endocann...

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Bibliographic Details
Main Authors: Arina I. Ponomarenko, Anna A. Tyrtyshnaia, Evgeny A. Pislyagin, Inessa V. Dyuizen, Ruslan M. Sultanov, Igor V. Manzhulo
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-80818-9