Histone Chaperone Jun Dimerization Protein 2 (JDP2): Role in Cellular Senescence and Aging

Transcription factor Jun dimerization protein 2 (JDP2) binds directly to histones and DNA, and inhibits p300-mediated acetylation of core histones and reconstituted nucleosomes that contain JDP2-recognition DNA sequences. The region of JDP2 that encompasses its histone-binding domain and DNA-binding...

Full description

Bibliographic Details
Main Authors: Yu-Chang Huang, Shigeo Saito, Kazunari Kzaushige Yokoyama
Format: Article
Language:English
Published: Wiley 2010-10-01
Series:Kaohsiung Journal of Medical Sciences
Subjects:
Arf
Online Access:http://www.sciencedirect.com/science/article/pii/S1607551X10700814