Natural biocombinatorics in the polyketide synthase genes of the actinobacterium Streptomyces avermitilis.

Modular polyketide synthases (PKSs) of bacteria provide an enormous reservoir of natural chemical diversity. Studying natural biocombinatorics may aid in the development of concepts for experimental design of genes for the biosynthesis of new bioactive compounds. Here we address the question of how...

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Bibliographic Details
Main Authors: Holger Jenke-Kodama, Thomas Börner, Elke Dittmann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-10-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC1592344?pdf=render