Functional Role of Parkin against Oxidative Stress in Neural Cells

BackgroundParkinson disease (PD) is caused by selective cell death of dopaminergic neurons in the substantia nigra. An early onset form of PD, autosomal recessive juvenile parkinsonism has been associated with a mutation in the parkin gene. The function of parkin is known to remove misfolding protei...

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Bibliographic Details
Main Authors: Minyoung Hwang, Ja-Myong Lee, Younghwa Kim, Dongho Geum
Format: Article
Language:English
Published: Academya Publishing Co. 2014-03-01
Series:Endocrinology and Metabolism
Subjects:
Online Access:http://e-enm.org/Synapse/Data/PDFData/2008ENM/enm-29-62.pdf