Interneuron hypomyelination is associated with cognitive inflexibility in a rat model of schizophrenia
Dysfunction of GABAergic neurons in the prefrontal cortex has been reported in schizophrenia. Here, the authors use the apomorphine-susceptible rat, which displays some schizophrenia-like behaviors, and show that interneurons in the medial prefrontal cortex are hypomyelinated, which may contribute t...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2020-05-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-020-16218-4 |