In silico models for evaluating proarrhythmic risk of drugs
Safety evaluation of drugs requires examination of the risk of generating Torsade de Pointes (TdP) because it can lead to sudden cardiac death. Until recently, the QT interval in the electrocardiogram (ECG) has been used in the evaluation of TdP risk because the QT interval is known to be associated...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
AIP Publishing LLC
2020-06-01
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Series: | APL Bioengineering |
Online Access: | http://dx.doi.org/10.1063/1.5132618 |