Neopterin, Dihydroneopterin, Tetrahydroneopterin: Different Structures-Increasing Capacity Cleaving the Porphyrin in Heme Proteins

Neopterin, 7,8-dihydroneopterin and 5,6,7,8-terahydroneopterm are secreted by human macrophages after activation by interferon-γ. The biological stability of the reduced pterins is less than one hour and therefore distinctly lower than that of neopterin. Ptendme derivatives are known to act as enhan...

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Bibliographic Details
Main Authors: Horejsi Renate, Möller Reinhard, Tafeit Erwin, Reibnegger Gilbert
Format: Article
Language:English
Published: De Gruyter 2002-11-01
Series:Pteridines
Subjects:
Online Access:https://doi.org/10.1515/pteridines.2002.13.4.115