Estradiol promotes trophoblast viability and invasion by activating SGK1

Background: 17β-Estradiol (E2) is a critical regulator of trophoblast function during pregnancy. Serum- and glucocorticoid-inducible kinase (SGK1) has been shown to regulate specific cellular targets downstream of E2. However, whether and how SGK1 directly mediates the regulatory effects of E2 on tr...

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Bibliographic Details
Main Authors: Wei-Hua He, Meng-Meng Jin, Ai-Ping Liu, Ying Zhou, Xiao-Ling Hu, Yi-Min Zhu, Ai-Xia Liu
Format: Article
Language:English
Published: Elsevier 2019-09-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S075333221931025X