N-terminal phosphorylation of the dopamine transporter is required for amphetamine-induced efflux.

N-terminal phosphorylation of the dopamine transporter is required for amphetamine-induced efflux.

Amphetamine (AMPH) elicits its behavioral effects by acting on the dopamine (DA) transporter (DAT) to induce DA efflux into the synaptic cleft. We previously demonstrated that a human DAT construct in which the first 22 amino acids were truncated was not phosphorylated by activation of protein kinas...

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Bibliographic Details
Main Authors: Habibeh Khoshbouei, Namita Sen, Bipasha Guptaroy, L 'Aurelle Johnson, David Lund, Margaret E Gnegy, Aurelio Galli, Jonathan A Javitch
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2004-03-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.0020078

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https://doi.org/10.1371/journal.pbio.0020078

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