Expression and bioactivity analysis of TNF30, a TNFα nanobody, in Escherichia coli

Expression and bioactivity analysis of TNF30, a TNFα nanobody, in Escherichia coli

Antibodies and antagonists targeting tumour necrosis factor alpha (TNFα) have become a number of the best-selling anti-inflammatory drugs. The nanobody is a single domain antibody derived from the variable domain of a heavy-chain antibody. However, so far, there are still no reports on the recombina...

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Bibliographic Details
Main Authors: Qian Li, Zhi Miao, Xue-Gang Luo, Jian Zhao, Ya-Jian Song, Zhong-Yuan Li, Hao Zhou, Tong-Cun Zhang, Li-Song Mao
Format: Article
Language:English
Published: Taylor & Francis Group 2018-07-01
Series:Biotechnology & Biotechnological Equipment
Subjects:
Tumour necrosis factor
nanobody
recombinant expression
arthritis
Online Access:http://dx.doi.org/10.1080/13102818.2018.1480422

Internet

http://dx.doi.org/10.1080/13102818.2018.1480422

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