Sensory Neuropeptides and their Receptors Participate in Mechano-Regulation of Murine Macrophages

Sensory Neuropeptides and their Receptors Participate in Mechano-Regulation of Murine Macrophages

This study aimed to analyze if the sensory neuropeptide SP (SP) and the neurokinin receptor 1 (NK1R) are involved in macrophage mechano-transduction, similar to chondrocytes, and if alpha-calcitonin gene-related peptide (αCGRP) and the CGRP receptor (CRLR/Ramp1) show comparable activity. Mu...

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Bibliographic Details
Main Authors: Dominique Muschter, Anna-Sophie Beiderbeck, Tanja Späth, Christian Kirschneck, Agnes Schröder, Susanne Grässel
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:International Journal of Molecular Sciences
Subjects:
cyclic stretch
mechan-oregulation
murine macrophages
substance P
alpha-calcitonin gene-related peptide
neurokinin receptor
CGRP receptor
destabilized medial meniscus
Online Access:https://www.mdpi.com/1422-0067/20/3/503

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https://www.mdpi.com/1422-0067/20/3/503

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