Colombian Scorpion <i>Centruroides margaritatus</i>: Purification and Characterization of a Gamma Potassium Toxin with Full-Block Activity on the hERG1 Channel

Colombian Scorpion <i>Centruroides margaritatus</i>: Purification and Characterization of a Gamma Potassium Toxin with Full-Block Activity on the hERG1 Channel

The Colombian scorpion <i>Centruroides margaritatus</i> produces a venom considered of low toxicity. Nevertheless, there are known cases of envenomation resulting in cardiovascular disorders, probably due to venom components that target ion channels. Among them, the <i>human</i&...

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Bibliographic Details
Main Authors: José Beltrán-Vidal, Edson Carcamo-Noriega, Nina Pastor, Fernando Zamudio-Zuñiga, Jimmy Alexander Guerrero-Vargas, Santiago Castaño, Lourival Domingos Possani, Rita Restano-Cassulini
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Toxins
Subjects:
<i>Centruroides margaritatus</i>
CmERG1
CnERG1
Electrophysiology
ERG toxin
ERG channel
Online Access:https://www.mdpi.com/2072-6651/13/6/407

Internet

https://www.mdpi.com/2072-6651/13/6/407

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