Plasma trimethylamine N-oxide and its metabolic precursors and risk of mortality, cardiovascular and renal disease in individuals with type 2-diabetes and albuminuria.

Plasma trimethylamine N-oxide and its metabolic precursors and risk of mortality, cardiovascular and renal disease in individuals with type 2-diabetes and albuminuria.

<h4>Aims</h4>The trimethylamine N-oxide (TMAO) pathway is related to intestinal microbiota and has been associated to risk of cardiovascular disease (CVD). We investigated associations between four plasma metabolites in the TMAO pathway and risk of all-cause mortality, CVD and deteriorat...

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Main Authors: Signe Abitz Winther, Jens Christian Øllgaard, Tine Willum Hansen, Bernt Johan von Scholten, Henrik Reinhard, Tarunveer Singh Ahluwalia, Zeneng Wang, Peter Gæde, Hans-Henrik Parving, Stanley Hazen, Oluf Pedersen, Peter Rossing
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0244402

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https://doi.org/10.1371/journal.pone.0244402

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