Dodging COVID-19 infection: low expression and localization of ACE2 and TMPRSS2 in multiple donor-derived lines of human umbilical cord-derived mesenchymal stem cells

Dodging COVID-19 infection: low expression and localization of ACE2 and TMPRSS2 in multiple donor-derived lines of human umbilical cord-derived mesenchymal stem cells

Abstract Background Mesenchymal stem cells derived from human umbilical cord (hUC-MSCs) have immunomodulatory properties that are of interest to treat novel coronavirus disease 2019 (COVID-19). Leng et al. recently reported that hUC-MSCs derived from one donor negatively expressed Angiotensin-Conver...

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Bibliographic Details
Main Authors: Jonathan J. Hernandez, Doyle E. Beaty, Logan L. Fruhwirth, Ana P. Lopes Chaves, Neil H. Riordan
Format: Article
Language:English
Published: BMC 2021-04-01
Series:Journal of Translational Medicine
Subjects:
ACE2 expression
TMPRSS2 expression
COVID-19
SARS-Cov2
Mesenchymal stem cells
HUC-MSC
Online Access:https://doi.org/10.1186/s12967-021-02813-6

Internet

https://doi.org/10.1186/s12967-021-02813-6

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