Parathyroid hormone (1-34) ameliorates cartilage degeneration and subchondral bone deterioration in collagenase-induced osteoarthritis model in mice

Aims: Parathyroid hormone (PTH) (1-34) exhibits potential in preventing degeneration in both cartilage and subchondral bone in osteoarthritis (OA) development. We assessed the effects of PTH (1-34) at different concentrations on bone and cartilage metabolism in a collagenase-induced mouse model of O...

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Bibliographic Details
Main Authors: Li-tao Shao, Yu Gou, Jia-kang Fang, Yun-peng Hu, Qiang-qiang Lian, Yu-ying Zhang, Yu-dan Wang, Fa-ming Tian, Liu Zhang
Format: Article
Language:English
Published: The British Editorial Society of Bone & Joint Surgery 2020-10-01
Series:Bone & Joint Research
Subjects:
Online Access:https://online.boneandjoint.org.uk/doi/epdf/10.1302/2046-3758.910.BJR-2020-0018.R1