Comparison of Molecular Recognition of Trimethyllysine and Trimethylthialysine by Epigenetic Reader Proteins

Comparison of Molecular Recognition of Trimethyllysine and Trimethylthialysine by Epigenetic Reader Proteins

Gaining a fundamental insight into the biomolecular recognition of posttranslationally modified histones by epigenetic reader proteins is of crucial importance to understanding the regulation of the activity of human genes. Here, we seek to establish whether trimethylthialysine, a simple trimethylly...

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Bibliographic Details
Main Authors: Jordi C. J. Hintzen, Jordi Poater, Kiran Kumar, Abbas H. K. Al Temimi, Bas J. G. E. Pieters, Robert S. Paton, F. Matthias Bickelhaupt, Jasmin Mecinović
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Molecules
Subjects:
epigenetics
histone
lysine methylation
molecular recognition
noncovalent interactions
Online Access:https://www.mdpi.com/1420-3049/25/8/1918

Internet

https://www.mdpi.com/1420-3049/25/8/1918

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