Plasma metabolomics of presymptomatic PSEN1‐H163Y mutation carriers: a pilot study
Abstract Background and Objective PSEN1‐H163Y carriers, at the presymptomatic stage, have reduced 18FDG‐PET binding in the cerebrum of the brain (Scholl et al., Neurobiol Aging 32:1388–1399, 2011). This could imply dysfunctional energy metabolism in the brain. In this study, plasma of presymptomatic...
Main Authors: | Karthick Natarajan, Abbe Ullgren, Behzad Khoshnood, Charlotte Johansson, José M. Laffita‐Mesa, Josef Pannee, Henrik Zetterberg, Kaj Blennow, Caroline Graff |
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Format: | Article |
Language: | English |
Published: |
Wiley
2021-03-01
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Series: | Annals of Clinical and Translational Neurology |
Online Access: | https://doi.org/10.1002/acn3.51296 |
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