Overexpression of dilp2 causes nutrient-dependent semi-lethality in Drosophila

Overexpression of dilp2 causes nutrient-dependent semi-lethality in Drosophila

Insulin/insulin-like growth factor (IGF) plays an important role as a systemic regulator of metabolism in multicellular organisms. Hyperinsulinemia, a high level of blood insulin, is often associated with impaired physiological conditions such as hypoglycemia, insulin resistance, and diabetes. Howev...

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Bibliographic Details
Main Authors: Yukiko eSato-Miyata, Keigo eMuramatsu, Masabumi eFunakoshi, Manabu eTsuda, Toshiro eAigaki
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-04-01
Series:Frontiers in Physiology
Subjects:
Autophagy
Growth
Hyperinsulinism
Metabolism
Nutritional Status
Insulin-like growth factor
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00147/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00147/full

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