[18F]FDG, [11C]PiB, and [18F]AV-1451 PET Imaging of Neurodegeneration in Two Subjects With a History of Repetitive Trauma and Cognitive Decline

Background: Trauma-related neurodegeneration can be difficult to differentiate from multifactorial neurodegenerative syndromes, both clinically and radiographically. We have initiated a protocol for in vivo imaging of patients with suspected TBI-related neurodegeneration utilizing volumetric MRI and...

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Bibliographic Details
Main Authors: David O. Okonkwo, Ross C. Puffer, Davneet S. Minhas, Sue R. Beers, Kathryn L. Edelman, Jane Sharpless, Charles M. Laymon, Brian J. Lopresti, Steven Benso, Ava M. Puccio, Sudhir Pathak, Milos D. Ikonomovic, Joseph M. Mettenburg, Walter Schneider, Chester A. Mathis, James M. Mountz
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Neurology
Subjects:
TBI
CTE
PET
PiB
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2019.00831/full