Gly-tRF enhances LCSC-like properties and promotes HCC cells migration by targeting NDFIP2

Gly-tRF enhances LCSC-like properties and promotes HCC cells migration by targeting NDFIP2

Abstract Background Accumulating evidence demonstrates that tRFs (tRNA-derived small RNA fragments) and tiRNAs (tRNA-derived stress-induced RNA), an emerging category of regulatory RNA molecules derived from transfer RNAs (tRNAs), are dysregulated in in various human cancer types and play crucial ro...

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Bibliographic Details
Main Authors: Yongqiang Zhou, Jinjing Hu, Lu Liu, Mengchao Yan, Qiyu Zhang, Xiaojing Song, Yan Lin, Dan Zhu, Yongjian Wei, Zongli Fu, Liming Hu, Yue Chen, Xun Li
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Cancer Cell International
Subjects:
Hepatocellular carcinoma
Liver cancer stem cells
tRNA-derived fragments
NDFIP2
EMT
AKT
Online Access:https://doi.org/10.1186/s12935-021-02102-8

Internet

https://doi.org/10.1186/s12935-021-02102-8

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