Characterization of phenyl pyrimidine derivatives that inhibit cytomegalovirus immediate-early gene expression

Background Previously, we established a reporter cell line for human cytomegalovirus and screened anti-human cytomegalovirus compounds using the cell line. In this study, we characterized one of the identified compounds, 2,4-diamino-6–(4-methoxyphenyl)pyrimidine (coded as 35C10). Methods 50% Effecti...

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Bibliographic Details
Main Authors: Koh-Hei Yamada, Ryuichi Majima, Toyofumi Yamaguchi, Naoki Inoue
Format: Article
Language:English
Published: SAGE Publishing 2018-03-01
Series:Antiviral Chemistry & Chemotherapy
Online Access:https://doi.org/10.1177/2040206618763193