Maintenance of Primary Hepatocyte Functions In Vitro by Inhibiting Mechanical Tension-Induced YAP Activation

Summary: Hepatocytes are the primary functional cells of the liver, performing its metabolic, detoxification, and endocrine functions. Functional hepatocytes are extremely valuable in drug discovery and evaluation, as well as in cell therapy for liver diseases. However, it has been a long-standing c...

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Bibliographic Details
Main Authors: Pingxin Sun, Guanyu Zhang, Xiaohui Su, Caixia Jin, Bing Yu, Xinlu Yu, Zhuman Lv, Haoxin Ma, Mingliang Zhang, Wanguo Wei, Wenlin Li
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719314615