Reinforcement learning derived chemotherapeutic schedules for robust patient-specific therapy

Abstract The in-silico development of a chemotherapeutic dosing schedule for treating cancer relies upon a parameterization of a particular tumour growth model to describe the dynamics of the cancer in response to the dose of the drug. In practice, it is often prohibitively difficult to ensure the v...

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Bibliographic Details
Main Authors: Brydon Eastman, Michelle Przedborski, Mohammad Kohandel
Format: Article
Language:English
Published: Nature Publishing Group 2021-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-97028-6