An association between crypt apoptotic bodies and mucosal flattening in celiac disease patients exposed to dietary gluten

Abstract Background Celiac disease (CD) is characterized histologically by inflammation and villous atrophy. Villous atrophy is thought to result from a disruption of epithelial cellular proliferation and death. Epithelial cells in intestinal mucosa normally proliferate in the crypts and migrate tow...

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Bibliographic Details
Main Authors: Michael Lee, Shane Betman, Alina Iuga, Hui-Min Yang, Jude Fleming, Peter H. R. Green, Benjamin Lebwohl, Stephen M. Lagana
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Diagnostic Pathology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13000-019-0878-1