Scutellarein selectively targets multiple myeloma cells by increasing mitochondrial superoxide production and activating intrinsic apoptosis pathway

Scutellarein selectively targets multiple myeloma cells by increasing mitochondrial superoxide production and activating intrinsic apoptosis pathway

Objectives: Scutellarein is a flavonoid monomer found in traditional Chinese medicine such as Scutellaria barbata. This study aimed to investigate the cytotoxic effect of scutellarein treatment on multiple myeloma (MM) cells. Methods: circulating B lymphocytes (CBL) isolated from healthy donors’ per...

Full description

Bibliographic Details
Main Authors: Lin Shi, Yi Wu, Dian liang LV, Lei Feng
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Scutellarein
Multiple myeloma
Superoxide
Mitochondria
ROS
NADPH
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332218344780

Internet

http://www.sciencedirect.com/science/article/pii/S0753332218344780

Similar Items