Lessons from Genome-Wide Search for Disease-Related Genes with Special Reference to HLA-Disease Associations
The relationships between diseases and genetic factors are by no means uniform. Single-gene diseases are caused primarily by rare mutations of specific genes. Although each single-gene disease has a low prevalence, there are an estimated 5000 or more such diseases in the world. In contrast, multifac...
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| Format: | Article |
| Language: | English |
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MDPI AG
2014-02-01
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| Series: | Genes |
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| Online Access: | http://www.mdpi.com/2073-4425/5/1/84 |