α-Mangostin extracted from the pericarp of the mangosteen (<it>Garcinia mangostana </it>Linn) reduces tumor growth and lymph node metastasis in an immunocompetent xenograft model of metastatic mammary cancer carrying a p53 mutation

<p>Abstract</p> <p>Background</p> <p>The mangosteen fruit has a long history of medicinal use in Chinese and Ayurvedic medicine. Recently, the compound α-mangostin, which is isolated from the pericarp of the fruit, was shown to induce cell death in various types of canc...

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Bibliographic Details
Main Authors: Okuno Yasushi, Akamatsu Kanako, Kurose Hitomi, Morimoto Junji, Iinuma Munekazu, Shibata Masa-Aki, Akao Yukihiro, Otsuki Yoshinori
Format: Article
Language:English
Published: BMC 2011-06-01
Series:BMC Medicine
Online Access:http://www.biomedcentral.com/1741-7015/9/69