MGL2 Dermal dendritic cells are sufficient to initiate contact hypersensitivity in vivo.

BACKGROUND:Dendritic cells (DCs) are the most potent antigen-presenting cells in the mammalian immune system. In the skin, epidermal Langerhans cells (LCs) and dermal dendritic cells (DDCs) survey for invasive pathogens and present antigens to T cells after migration to the cutaneous lymph nodes (LN...

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Bibliographic Details
Main Authors: Yosuke Kumamoto, Kaori Denda-Nagai, Satoshi Aida, Nobuaki Higashi, Tatsuro Irimura
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2680031?pdf=render