Skip Regulates TGF-β1-Induced Extracellular Matrix Degrading Proteases Expression in Human PC-3 Prostate Cancer Cells

Purpose. To determine whether Ski-interacting protein (SKIP) regulates TGF-β1-stimulated expression of urokinase-type plasminogen activator (uPA), matrix metalloproteinase-9 (MMP-9), and uPA Inhibitor (PAI-1) in the androgen-independent human prostate cancer cell model. Materials and Methods. PC-3 p...

Full description

Bibliographic Details
Main Authors: Victor Villar, Jelena Kocic, Juan F. Santibanez
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:Prostate Cancer
Online Access:http://dx.doi.org/10.1155/2013/398253