Establishment of a Suspension MDBK Cell Line in Serum-Free Medium for Production of Bovine Alphaherpesvirus-1

The Madin–Darby bovine kidney (MDBK) cell line is currently used for the production of bovine alphaherpesvirus-1 (BoHV-1) vaccine. For the purpose of vaccine manufacturing, suspension cells are preferred over adherent ones due to simplified sub-cultivation and an easier scale-up process, both of whi...

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Bibliographic Details
Main Authors: Pengpeng Wang, Shulin Huang, Chengwu Hao, Zhanhui Wang, Haoran Zhao, Mengyao Liu, Xinrui Tian, Letu Ge, Wenxue Wu, Chen Peng
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Vaccines
Subjects:
Online Access:https://www.mdpi.com/2076-393X/9/9/1006