Current Status and Future Prospects of Clinically Exploiting Cancer-specific Metabolism—Why Is Tumor Metabolism Not More Extensively Translated into Clinical Targets and Biomarkers?

Current Status and Future Prospects of Clinically Exploiting Cancer-specific Metabolism—Why Is Tumor Metabolism Not More Extensively Translated into Clinical Targets and Biomarkers?

Tumor cells exhibit a specialized metabolism supporting their superior ability for rapid proliferation, migration, and apoptotic evasion. It is reasonable to assume that the specific metabolic needs of the tumor cells can offer an array of therapeutic windows as pharmacological disturbance may derai...

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Bibliographic Details
Main Authors: Magesh Muthu, Anders Nordström
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:International Journal of Molecular Sciences
Subjects:
translational medicine
metabolomics
metabolism
cancer
tumor
biomarker
drug discovery
metabolic homeostasis
Online Access:http://www.mdpi.com/1422-0067/20/6/1385

Internet

http://www.mdpi.com/1422-0067/20/6/1385

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