The Aminopyridinol Derivative BJ-1201 Protects Murine Hippocampal Cells against Glutamate-Induced Neurotoxicity via Heme Oxygenase-1

The Aminopyridinol Derivative BJ-1201 Protects Murine Hippocampal Cells against Glutamate-Induced Neurotoxicity via Heme Oxygenase-1

Glutamate is the major excitatory neurotransmitter in the brain. It can cause neuronal cell damage in the context of oxidative stress. BJ-1201 is a derivative of the compound aminopyridinol, which is known for its antioxidant activity. In this study, we examined the effect of BJ-1201, a 6-(diphenyla...

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Bibliographic Details
Main Authors: Dong-Sung Lee, Tae-Gyu Nam, Byeong-Seon Jeong, Gil-Saeng Jeong
Format: Article
Language:English
Published: MDPI AG 2016-05-01
Series:Molecules
Subjects:
aminopyridinol compound BJ-1201
neuroprotection
aminopyridinol HT22
heme oxygenase-1
nuclear transcription factor erythroid-2 related factor 2
Online Access:http://www.mdpi.com/1420-3049/21/5/594

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http://www.mdpi.com/1420-3049/21/5/594

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