Review: A review on classical and atypical scrapie in caprine: Prion protein gene polymorphisms and their role in the disease

Scrapie is a naturally occurring transmissible spongiform encephalopathy in sheep and goat. It has been known for ~250 years and is characterised by the accumulation of an abnormal isoform of a host-encoded prion protein that leads to progressive neurodegeneration and death. Scrapie is recognised in...

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Bibliographic Details
Main Authors: L. Curcio, C. Sebastiani, P. Di Lorenzo, E. Lasagna, M. Biagetti
Format: Article
Language:English
Published: Elsevier 2016-01-01
Series:Animal
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1751731116000653