A Comparison between Enriched and Nonenriched Enrollment Randomized Withdrawal Trials of Opioids for Chronic Noncancer Pain

An enriched enrollment randomized withdrawal (EERW) trial design has been advocated to be useful for the study of drugs that are beneficial to only a fraction of the individuals who take them. Some investigators defend the use of enrichment designs for opioids in chronic noncancer pain (CNCP), reaso...

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Bibliographic Details
Main Authors: Andrea D Furlan, Luis E Chaparro, Emma Irvin, Angela Mailis-Gagnon
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Pain Research and Management
Online Access:http://dx.doi.org/10.1155/2011/465281