Metastatic Tumor Cells Exploit Their Adhesion Repertoire to Counteract Shear Forces during Intravascular Arrest

Summary: Cancer metastasis is a process whereby a primary tumor spreads to distant organs. We have demonstrated previously that blood flow controls the intravascular arrest of circulating tumor cells (CTCs) through stable adhesion to endothelial cells. We now aim to define the contribution of cell a...

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Bibliographic Details
Main Authors: Naël Osmani, Gautier Follain, María J. García León, Olivier Lefebvre, Ignacio Busnelli, Annabel Larnicol, Sébastien Harlepp, Jacky G. Goetz
Format: Article
Language:English
Published: Elsevier 2019-09-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719310186