Heparanase upregulation from adipocyte associates with inflammation and endothelial injury in diabetic condition

Heparanase upregulation from adipocyte associates with inflammation and endothelial injury in diabetic condition

Abstract Background Diabetes Mellitus (DM) is one of the metabolic diseases which leads to fatty tissue injury, and consequently inducing lipotoxicity and cellular senescence. This condition contributes to endothelial dysfunction with chronic inflammation and organ damage. Heparanase which has a rol...

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Bibliographic Details
Main Authors: Nur Arfian, Wiwit Ananda Wahyu Setyaningsih, Muhammad Mansyur Romi, Dwi Cahyani Ratna Sari
Format: Article
Language:English
Published: BMC 2019-12-01
Series:BMC Proceedings
Subjects:
Diabetes mellitus
Heparanase
MCP-1
Inflammation
Endothelial injury
Online Access:https://doi.org/10.1186/s12919-019-0181-x

Internet

https://doi.org/10.1186/s12919-019-0181-x

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