Rapamycin Attenuated Cardiac Hypertrophy Induced by Isoproterenol and Maintained Energy Homeostasis via Inhibiting NF-κB Activation

Rapamycin, also known as sirolimus, is an immunosuppressant drug used to prevent rejection organ (especially kidney) transplantation. However, little is known about the role of Rapa in cardiac hypertrophy induced by isoproterenol and its underlying mechanism. In this study, Rapa was administrated in...

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Bibliographic Details
Main Authors: Xi Chen, Siyu Zeng, Jian Zou, Yanfang Chen, Zhongbao Yue, Ying Gao, Luankun Zhang, Weiwei Cao, Peiqing Liu
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2014/868753