Tetrahydrobiopterin Plays a Functionally Significant Role in Lipogenesis in the Oleaginous Fungus Mortierella alpina

Tetrahydrobiopterin Plays a Functionally Significant Role in Lipogenesis in the Oleaginous Fungus Mortierella alpina

Tetrahydrobiopterin (BH4) is well-known as a cofactor of phenylalanine hydroxylase (PAH) and nitric oxide synthase (NOS), but its exact role in lipogenesis is unclear. In this study, the GTP cyclohydrolase I (GTPCH) gene was overexpressed to investigate the role of BH4 in lipogenesis in oleaginous f...

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Bibliographic Details
Main Authors: Hongchao Wang, Chen Zhang, Haiqin Chen, Zhennan Gu, Jianxin Zhao, Hao Zhang, Yong Q. Chen, Wei Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Microbiology
Subjects:
Mortierella alpine
tetrahydrobiopterin
GTP cyclohydrolase I
NADPH
lipogenesis
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.00250/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2020.00250/full

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