In vivo Hox binding specificity revealed by systematic changes to a single cis regulatory module

Hox proteins are expressed in partially overlapping regions to inform development along the embryo’s head-tail axis. Here the authors analyse a cis regulatory module directly regulated by seven different Drosophila Hox proteins to uncover how different Hox class proteins differentially control its e...

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Bibliographic Details
Main Authors: Carlos Sánchez-Higueras, Chaitanya Rastogi, Roumen Voutev, Harmen J. Bussemaker, Richard S. Mann, James C.-G. Hombría
Format: Article
Language:English
Published: Nature Publishing Group 2019-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-11416-1