Dopamine D1 receptor agonist A68930 attenuates acute kidney injury by inhibiting NLRP3 inflammasome activation

Renal ischemia/reperfusion (I/R) injury is a major cause of acute kidney injury (AKI), characterized by tubulointerstitial inflammation. Currently, progress in developing effective therapies to prevent or ameliorate AKI by anti-inflammation remains slow. Emerging studies have suggested that NLRP3 (t...

Full description

Bibliographic Details
Main Authors: Jing-Yuan Cao, Le-Ting Zhou, Zuo-Lin Li, Yan Yang, Bi-Cheng Liu, Hong Liu
Format: Article
Language:English
Published: Elsevier 2020-07-01
Series:Journal of Pharmacological Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861320300414