The p75 neurotrophin receptor is a central regulator of glioma invasion.

The invasive nature of cancers in general, and malignant gliomas in particular, is a major clinical problem rendering tumors incurable by conventional therapies. Using a novel invasive glioma mouse model established by serial in vivo selection, we identified the p75 neurotrophin receptor (p75(NTR))...

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Bibliographic Details
Main Authors: Angela L M Johnston, Xueqing Lun, Jennifer J Rahn, Abdelhamid Liacini, Limei Wang, Mark G Hamilton, Ian F Parney, Barbara L Hempstead, Stephen M Robbins, Peter A Forsyth, Donna L Senger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-08-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC1939884?pdf=render