The p75 neurotrophin receptor is a central regulator of glioma invasion.
The invasive nature of cancers in general, and malignant gliomas in particular, is a major clinical problem rendering tumors incurable by conventional therapies. Using a novel invasive glioma mouse model established by serial in vivo selection, we identified the p75 neurotrophin receptor (p75(NTR))...
Main Authors: | , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2007-08-01
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Series: | PLoS Biology |
Online Access: | http://europepmc.org/articles/PMC1939884?pdf=render |