A requirement for FGF signalling in the formation of primitive streak-like intermediates from primitive ectoderm in culture.

<h4>Background</h4>Embryonic stem (ES) cells hold considerable promise as a source of cells with therapeutic potential, including cells that can be used for drug screening and in cell replacement therapies. Differentiation of ES cells into the somatic lineages is a regulated process; bef...

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Bibliographic Details
Main Authors: Zhiqiang Zheng, Robb U de Iongh, Peter D Rathjen, Joy Rathjen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-09-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20838439/?tool=EBI