A 3D Printed Self-Sustainable Cell-Encapsulation Drug Delivery Device for Periocular Transplant-Based Treatment of Retinal Degenerative Diseases

A 3D Printed Self-Sustainable Cell-Encapsulation Drug Delivery Device for Periocular Transplant-Based Treatment of Retinal Degenerative Diseases

Self-sustainable release of brain-derived neurotrophic factor (BDNF) to the retina using minimally invasive cell-encapsulation devices is a promising approach to treat retinal degenerative diseases (RDD). Herein, we describe such a self-sustainable drug delivery device with human retinal pigment epi...

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Bibliographic Details
Main Authors: Hideto Kojima, Bibek Raut, Li-Jiun Chen, Nobuhiro Nagai, Toshiaki Abe, Hirokazu Kaji
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Micromachines
Subjects:
retinal degenerative disease
cell-encapsulation device
periocular implant
growth factors
brain-derived neurotrophic factor (BDNF)
cell sheet engineering
Online Access:https://www.mdpi.com/2072-666X/11/4/436

Internet

https://www.mdpi.com/2072-666X/11/4/436

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