New insights into the pathogenesis of leprosy: contribution of subversion of host cell metabolism to bacterial persistence, disease progression, and transmission [version 1; peer review: 2 approved]
Chronic infection by the obligate intracellular pathogen Mycobacterium leprae may lead to the development of leprosy. Of note, in the lepromatous clinical form of the disease, failure of the immune system to constrain infection allows the pathogen to reproduce to very high numbers with minimal clini...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
F1000 Research Ltd
2020-01-01
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Series: | F1000Research |
Online Access: | https://f1000research.com/articles/9-70/v1 |