Curcumol Inhibits Growth and Induces Apoptosis of Colorectal Cancer LoVo Cell Line via IGF-1R and p38 MAPK Pathway

Curcumol Inhibits Growth and Induces Apoptosis of Colorectal Cancer LoVo Cell Line via IGF-1R and p38 MAPK Pathway

Curcumol, isolated from the traditional medical plant Rhizoma Curcumae, is the bioactive component of Zedoary oil, whose potential anti-tumor effect has attracted considerable attention in recent years. Though many researchers have reported curcumol and its bioactivity, the potential molecular mecha...

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Bibliographic Details
Main Authors: Juan Wang, Fengxiang Huang, Zhun Bai, Bixia Chi, Jiacai Wu, Xu Chen
Format: Article
Language:English
Published: MDPI AG 2015-08-01
Series:International Journal of Molecular Sciences
Subjects:
curcumol
colorectal cancer
anti-tumor
IGF-1R
p38 MAPK
Online Access:http://www.mdpi.com/1422-0067/16/8/19851

Internet

http://www.mdpi.com/1422-0067/16/8/19851

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